Solubility and Bioavailability
Diindolylmethane is a lipophilic oil-soluble compound. Similar to other oil-soluble phytochemicals, such as lycopene and lutein, the presence of vegetable oil and other lipophilic compounds, such as phosphatidylcholine, that aid in the formation of absorption micelles within the gastrointestinal tract, greatly increase the bioavailability of DIM upon oral administration. Most of the preclinical animal studies and some of the human clinical trials conducted with DIM have consisted of DIM co-administered with vegetable oils. Some of the formulations have additionally contained phosphatidylcholine and other lipophilic excipients for enhanced absorption. When formulated correctly, Diindolylmethane is a highly bioavailable compound.
News Brief from
Diindolylmethane Immune Support Formula has been launched with technology exclusively
licensed from UC Berkeley as a fund-raiser for nature-based cancer therapeutics research. For
more information about this formula, please visit:
Diindolylmethane Information Resource Center